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Frequent Microsatellite Instabilities and Analyses of the Related Genes in Familial Gastric Cancers

Microsatellite instability or replication error seems to be related to defective DNA mismatch repair genes, such as hMSH2, hMLH1, hPMS1 and hPMS2, which have been identified as causative genes of hereditary nonpolyposis colorectal cancers (HNPCC). Recently, it was reported that mutations at the simp...

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Detalles Bibliográficos
Autores principales: Akiyama, Yoshimitsu, Nagasaki, Hiromi, Nihei, Zenro, Iwama, Takeo, Nomizu, Tadashi, Utsunomiya, Joji, Yuasa, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921144/
https://www.ncbi.nlm.nih.gov/pubmed/8766523
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00265.x