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Induction of MAGE Genes in Lymphoid Cells by the Demethylating Agent 5‐Aza‐2′‐deoxycytidine

MAGE genes encoding tumor antigens recognized by cytotoxic T lymphocytes are appropriate target molecules for specific immunotherapy of cancer. We have investigated whether the demethylating agent 5‐aza‐2′‐deoxycytidine (DAC) induces MAGE‐1, ‐2, ‐3, and ‐6 in normal and malignant lymphoid cells. DAC...

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Detalles Bibliográficos
Autores principales: Shichijo, Shigeki, Yamada, Akira, Sagawa, Kimitaka, Iwamoto, Osamu, Sakata, Motoko, Nagai, Kojiro, Itoh, Kyogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921158/
https://www.ncbi.nlm.nih.gov/pubmed/8698626
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00288.x