p53 Antisense Oligonucleotide Inhibits Growth of Human Colon Tumor and Normal Cell Lines

We examined the relationship between the expression of mutant p53 proteins and tumor cell growth using a p53 antisense oligonucleotide (5′‐CCCTGCTCCCCCCTGGCTCC‐3′). The oligonucleotide inhibited the growth of three human colon tumor cell lines (DLD‐1, SW620 and WiDr), which produce only mutant p53 p...

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Detalles Bibliográficos
Autores principales: Hirota, Yasuhide, Horiuchi, Tadashi, Akahane, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921161/
https://www.ncbi.nlm.nih.gov/pubmed/8698624
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00286.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921161/
https://www.ncbi.nlm.nih.gov/pubmed/8698624
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00286.x

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