Transduction of the Macrophage Colony‐stimulating Factor Gene into Human Multidrug Resistant Cancer Cells: Enhanced Therapeutic Efficacy of Monoclonal Anti‐P‐glycoprotein Antibody in Nude Mice

To develop a therapeutic modality for overcoming multidrug‐resistant (MDR) cancer with anti‐MDR1 antibody, we examined the effect of macrophage colony‐stimulating factor (M‐CSF) gene transfection into MDR AD10 cells on therapy of MDR cancer with anti‐MDR1 antihody (MRK17) in nude mice. MDR human ova...

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Detalles Bibliográficos
Autores principales: Sone, Saburo, Tsuruo, Takashi, Sato, Shigeo, Yano, Seiji, Nishioka, Yasuhiko, Shinohara, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921165/
https://www.ncbi.nlm.nih.gov/pubmed/8698627
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00289.x