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Transduction of the Macrophage Colony‐stimulating Factor Gene into Human Multidrug Resistant Cancer Cells: Enhanced Therapeutic Efficacy of Monoclonal Anti‐P‐glycoprotein Antibody in Nude Mice
To develop a therapeutic modality for overcoming multidrug‐resistant (MDR) cancer with anti‐MDR1 antibody, we examined the effect of macrophage colony‐stimulating factor (M‐CSF) gene transfection into MDR AD10 cells on therapy of MDR cancer with anti‐MDR1 antihody (MRK17) in nude mice. MDR human ova...
Autores principales: | Sone, Saburo, Tsuruo, Takashi, Sato, Shigeo, Yano, Seiji, Nishioka, Yasuhiko, Shinohara, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921165/ https://www.ncbi.nlm.nih.gov/pubmed/8698627 http://dx.doi.org/10.1111/j.1349-7006.1996.tb00289.x |
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