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Primary Malignant Lymphoma of the Brain: Demonstration of Frequent p16 and p15 Gene Deletions

The p16 (MTS‐1) gene, a candidate tumor suppressor gene, was examined by means of Southern blot, PCR‐SSCP (polymerase chain reaction‐single‐strand conformation polymorphism) and nucleotide analyses in 5 cases of primary malignant lymphoma of the brain. By Southern blot analysis, the p16 gene was fou...

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Detalles Bibliográficos
Autores principales: Kumanishi, Toshiro, Zhang, Shujing, Ichikawa, Tomio, Endo, Sumio, Washiyama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921166/
https://www.ncbi.nlm.nih.gov/pubmed/8698617
http://dx.doi.org/10.1111/j.1349-7006.1996.tb00279.x