Cargando…

Chemoprevention by Pravastatin, a 3‐Hydroxy‐3‐methylglutaryl‐coenzyme A Reductase Inhibitor, of N‐Methyl‐N‐nitrosourea‐induced Colon Carcinogenesis in F344 Rats

A potential chemopreventive action of pravastatin (Pr), a 3‐hydroxy‐3‐methylglutaryl‐coenzyme A redutase inhibitor, on colon carcinogenesis was evaluated in F344 rats. All rats at 7 weeks of age received an intrarectal dose of 2 mg of N‐methyl‐N‐nitrosourea 3 times weekly for 2 weeks in experiment I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Narisawa, Tomio, Morotomi, Masami, Fukaura, Yoko, Hasebe, Makiko, Ito, Michiko, Aizawa, Rika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1996
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921171/ https://www.ncbi.nlm.nih.gov/pubmed/8797885 http://dx.doi.org/10.1111/j.1349-7006.1996.tb02103.x

Ejemplares similares

A Very Low Dose of Green Tea Polyphenols in Drinking Water Prevents N‐Methyl‐N‐nitrosourea‐induced Colon Carcinogenesis in F344 Rats
por: Narisawa, Tomio, et al.
Publicado: (1993)

Chemoprevention of N‐Methylnitrosourea‐induced Colon Carcinogenesis by Ursodeoxycholic Acid‐5‐aminosalicylic Acid Conjugate in F344 Rats
por: Narisawa, Tomio, et al.
Publicado: (2002)

Chemoprevention by the Oxygenated Carotenoid β‐Cryptoxanthin of N‐Methylnitrosourea‐induced Colon Carcinogenesis in F344 Rats
por: Narisawa, Tomio, et al.
Publicado: (1999)

Prevention of N‐Methylnitrosourea‐induced Colon Tumorigenesis by Ursodeoxycholic Acid in F344 Rats
por: Narisawa, Tomio, et al.
Publicado: (1998)

Prevention of N‐Methylnitrosourea‐induced Colon Carcinogenesis in F344 Rats by Lycopene and Tomato Juice Rich in Lycopene
por: Narisawa, Tomio, et al.
Publicado: (1998)

Inhibitory Effect of Cryptoporic Acid E, a Product from Fungus Cryptoporus volvatus, on Colon Carcinogenesis Induced with N‐Methyl‐N‐Nitrosourea in Rats and with 1,2‐Dimethylhydrazine in Mice
por: Narisawa, Tomio, et al.
Publicado: (1992)

Inhibition of Mammary Tumors by Pretreatment with 17β‐Estradiol in F344 Rats Induced with N‐Methyl‐N‐nitrosourea
por: Ito, Akihiro, et al.
Publicado: (1994)

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
por: Friesen, Jon A, et al.
Publicado: (2004)

Hypercholesterolemia and 3-Hydroxy 3-Methylglutaryl Coenzyme A Reductase Regulation during Ageing
por: Trapani, Laura, et al.
Publicado: (2009)

Elevated Serum Growth Hormone Accelerates Gastric Tumorigenesis in F344 Rats after Treatment with N‐Methyl‐N‐nitrosourea in Their Drinking Water
por: Watanabe, Hiromitsu, et al.
Publicado: (1995)

Analysis of Autoantibodies to 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Using Different Technologies
por: Musset, Lucile, et al.
Publicado: (2014)

Varicose Remodeling of Veins Is Suppressed by 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Inhibitors
por: Eschrich, Johannes, et al.
Publicado: (2016)

3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: one disease - many faces
por: Grünert, Sarah C., et al.
Publicado: (2020)

Susceptibility to N-methyl-N-nitrosourea-induced retinal degeneration in different rat strains
por: Emoto, Yuko, et al.
Publicado: (2015)

Pediatric necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies
por: Liang, Wen-Chen, et al.
Publicado: (2017)

Correction to: 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: one disease - many faces
por: Grünert, Sarah C., et al.
Publicado: (2022)

Statin-Induced Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (Anti-HMGCR) Myopathy
por: Ghazal, Fatima, et al.
Publicado: (2023)

A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus
por: Stormo, Camilla, et al.
Publicado: (2012)

Chemopreventive Effects of Taurine on Diethylnitrosamine and Phenobarbitalinduced Hepatocarcinogenesis in Male F344 Rats
por: Okamoto, Kiyohisa, et al.
Publicado: (1996)

Induction of Glandular Stomach Cancers in C3H Mice Treated with N‐Methyl‐N‐nitrosourea in the Drinking Water
por: Tatematsu, Masae, et al.
Publicado: (1993)

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells
por: Elsabrouty, Rania, et al.
Publicado: (2013)

Management and long-term evolution of a patient with 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency
por: Muñoz-Bonet, Juan Ignacio, et al.
Publicado: (2017)

Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer()
por: Wei, Tzu-Tang, et al.
Publicado: (2016)

Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
por: Sasidhar, Manda V., et al.
Publicado: (2017)

Association of Common and Rare Genetic Variation in the 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
por: Ghouse, Jonas, et al.
Publicado: (2022)

First report of type 2 diabetes mellitus in an adult with 3-hydroxy-3-methylglutaryl coenzyme A lyase deficiency
por: Lai, Valerie, et al.
Publicado: (2023)

Case report: Diagnostic clues for anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase myopathy in pediatric patients
por: Watanuki, Keisuke, et al.
Publicado: (2023)

Studies on N-Ethyl-N-nitrosourea Mutagenesis in BALB/c Mice
por: Cho, Kyu-Hyuk, et al.
Publicado: (2008)

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells
por: Glynn, Sharon A, et al.
Publicado: (2008)

A Case of Dilated Cardiomyopathy Associated with 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG CoA) Lyase Deficiency
por: Leung, Alexander A. C., et al.
Publicado: (2009)

Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants
por: Li, Wei, et al.
Publicado: (2014)

Overexpressing 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGR) in the Lactococcal Mevalonate Pathway for Heterologous Plant Sesquiterpene Production
por: Song, Adelene Ai-Lian, et al.
Publicado: (2012)

Clinical Characteristics of Anti-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Antibodies in Chinese Patients with Idiopathic Inflammatory Myopathies
por: Ge, Yongpeng, et al.
Publicado: (2015)

Statins and Myotoxic Effects Associated With Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies: An Observational Study in Japan
por: Watanabe, Yurika, et al.
Publicado: (2015)

Genome-Wide Identification and Comparative Analysis of the 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Gossypium
por: Liu, Wei, et al.
Publicado: (2018)

Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl–Coenzyme A Reductase Inhibitor FR901512
por: Itoh, Hiroya, et al.
Publicado: (2017)

Juvenile idiopathic inflammatory myopathies with anti‐3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase antibodies in a Chinese cohort
por: Hou, Ying, et al.
Publicado: (2021)

Statin-naïve anti–3-hydroxy-3-methylglutaryl coenzyme A reductase antibody-positive necrotizing myopathy with heliotropic pseudoangioedema
por: Ortiz, Camila, et al.
Publicado: (2022)

3-Hydroxy-3-methylglutaryl coenzyme A reductase genes from Glycine max regulate plant growth and isoprenoid biosynthesis
por: Wang, Shuai, et al.
Publicado: (2023)

Mead acid supplementation does not rescue rats from cataract and retinal degeneration induced by N-methyl-N-nitrosourea
por: Emoto, Yuko, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2u0504kvham76d6kqqqpjjrprj