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Inhibition of Nucleolar Function and Morphological Change by Adriamycin Associated with Heat Shock Protein 70 Accumulation

Adriamycin (ADR) has been considered to target mainly DNA metabolism in the nucleus. Recently, we observed the nuclear translocation of heat shock protein 70 (HSP70) after ADR treatment. We examined which intranuclear changes might be related to this alteration of HSP70 localization. We found consid...

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Detalles Bibliográficos
Autores principales: Abe, Tetsuya, Fukamachi, Yukiyo, Kanazawa, Yohsuke, Furukawa, Hiroshi, Shimizu, Kenji, Hirano, Takeshi, Kasai, Hiroshi, Kashimura, Masamichi, Higashi, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921194/
https://www.ncbi.nlm.nih.gov/pubmed/8878457
http://dx.doi.org/10.1111/j.1349-7006.1996.tb02124.x