Establishment by Adriamycin Exposure of Multidrug‐resistant Rat Ascites Hepatoma AH130 Cells Showing Low DT‐diaphorase Activity and High Cross Resistance to Mitomycins

A resistant subline (AH130/5A) selected from rat hepatoma AH130 cells after exposure to adriamycin (ADM) showed remarkable resistance to multiple antitumor drugs, including mitomycin C (MMC) and porflromycin (PFM). PFM, vinblastine (VLB), and ADM accumulated in AH130/5A far less than in the parent A...

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Detalles Bibliográficos
Autores principales: Wakusawa, Shinya, Nakamura, Shigeo, Miyamoto, Ken‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921242/
https://www.ncbi.nlm.nih.gov/pubmed/9045901
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00306.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921242/
https://www.ncbi.nlm.nih.gov/pubmed/9045901
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00306.x

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