Induction of Aberrant Crypt Foci and Flat‐type Adenocarcinoma in the Colons of Dogs by N‐Ethyl‐N'‐nitro‐N‐nitrosoguanidine and Their Sequential Changes

Sequential endoscopic observation of dog colons was performed during colon carcinogenesis. Two beagle dogs were given suppositories containing N‐ethyl‐N'‐nitro‐N‐nitrosoguanidine (ENNG) every day for five months. In month 3, aberrant crypt foci (ACF), a putative preneoplastic lesion, were found...

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Detalles Bibliográficos
Autores principales: Sugiyama, Kenji, Oda, Yasushi, Otori, Kazuhiko, Kato, Shigeharu, Hasebe, Takahiro, Fujii, Takahiro, Tajiri, Hisao, Esumi, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921272/
https://www.ncbi.nlm.nih.gov/pubmed/9414653
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00311.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921272/
https://www.ncbi.nlm.nih.gov/pubmed/9414653
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00311.x

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