P16INK4Gene Mutations Are Relatively Frequent in Ampullary Carcinomas

A high incidence of gene mutations or deletions of P16INK4, a cell cycle regulator which inhibits the activity of cyclin‐dependent kinase 4/cyclin D complex and blocks the Gl‐to‐S transition, has been reported in pancreato‐biliary tract cancers. In order to investigateP16INK4 gene alterations in spo...

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Detalles Bibliográficos
Autores principales: Imai, Yasuo, Tsurutani, Naomi, Oda, Hideaki, Nakatsuru, Yoko, Inoue, Tohru, Ishikawa, Takatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921281/
https://www.ncbi.nlm.nih.gov/pubmed/9414654
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00312.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921281/
https://www.ncbi.nlm.nih.gov/pubmed/9414654
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00312.x

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