Promotion of Rat Hepatocarcinogenesis by Dimethylarsinic Acid: Association with Elevated Ornithine Decarboxylase Activity and Formation of 8‐Hydroxydeoxyguanosine in the Liver

Arsenicals are epidemiologicaUy significant chemicals in relation to induction of liver cancer in man. In the present study, we investigated the dose‐dependent promotion potential of dimethylarsinic acid (DMAA), a major metabolite of inorganic arsenicals in mammals, in a rat liver carcinogenesis mod...

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Detalles Bibliográficos
Autores principales: Wanibuchi, Hideki, Hori, Takaaki, Meenakshi, Vijayaraghavan, Ichihara, Toshio, Yamamoto, Shinji, Yano, Yoshihisa, Otani, Shuzo, Nakae, Dai, Konishi, Yoichi, Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921341/
https://www.ncbi.nlm.nih.gov/pubmed/9473732
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00343.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921341/
https://www.ncbi.nlm.nih.gov/pubmed/9473732
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00343.x

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