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Enhanced Topoisomerase I Activity and Increased Topoisomerase IIα Content in Cisplatin‐resistant Cancer Cell Lines

Although the combined effects of cisplatin (CDDP) and DNA topoisomerase (Topo) inhibitors have been described in recent literature, little is known about the combined effects and their biological basis in CDDP‐resistant cells. The aim of the present study was to elucidate the combined effect of CDDP...

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Detalles Bibliográficos
Autores principales: Minagawa, Yukihisa, Kigawa, Junzo, Irie, Takashi, Kanamori, Yasunobu, Itamochi, Hiroaki, Cheng, Xiusi, Terakawa, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921345/
https://www.ncbi.nlm.nih.gov/pubmed/9473741
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00352.x