The Role of Glucuronidation in 7‐Ethyl‐10‐hydroxycamptothecin Resistance in vitro

Although glucuronidation catalyzed by uridine 5′‐diphosphoglucuronosyltransferase (UGT) is a major pathway of drug inactivation in humans, glucuronidation in malignant cells has received little attention as a cause of anti‐cancer drug resistance. In this study, we tried to elucidate the role of SN‐3...

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Detalles Bibliográficos
Autores principales: Takahashi, Toshiaki, Fujiwara, Yasuhiro, Yamakido, Michio, Katoh, Osamu, Watanabe, Hiromitsu, Mackenzie, Peter I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921346/
https://www.ncbi.nlm.nih.gov/pubmed/9473740
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00351.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921346/
https://www.ncbi.nlm.nih.gov/pubmed/9473740
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00351.x

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