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Decreased Renal Accumulation of Biotinylated Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate after Administration of Avidin

Murine monoclonal antibodies (mAbs) such as A7 administered to humans induce a human anti‐mouse antibody response. Moreover, because Fab fragments of mAbs are able to penetrate target tumors easily, they may be more suitable than intact mAb to be carriers of anticancer agents such as neocarzinostati...

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Detalles Bibliográficos
Autores principales: Otsuji, Eigo, Yamaguchi, Toshiharu, Yamamoto, Kazuhito, Matsumura, Hiroomi, Tsuruta, Hiroshi, Yata, Yoshihiro, Nishi, Hiroshi, Okamoto, Kazuma, Kitamura, Kazuya, Takahashi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921355/
https://www.ncbi.nlm.nih.gov/pubmed/9119750
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00367.x