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Decreased Renal Accumulation of Biotinylated Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate after Administration of Avidin
Murine monoclonal antibodies (mAbs) such as A7 administered to humans induce a human anti‐mouse antibody response. Moreover, because Fab fragments of mAbs are able to penetrate target tumors easily, they may be more suitable than intact mAb to be carriers of anticancer agents such as neocarzinostati...
Autores principales: | Otsuji, Eigo, Yamaguchi, Toshiharu, Yamamoto, Kazuhito, Matsumura, Hiroomi, Tsuruta, Hiroshi, Yata, Yoshihiro, Nishi, Hiroshi, Okamoto, Kazuma, Kitamura, Kazuya, Takahashi, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921355/ https://www.ncbi.nlm.nih.gov/pubmed/9119750 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00367.x |
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