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Dose‐dependent Induction of Both Pepsinogen‐altered Pyloric Glands and Adenocarcinomas in the Glandular Stomach of C3H Mice Treated with N‐Methyl‐N‐nitrosourea

The dose‐response relation for the appearance of pepsinogen isozyme 1 (Pg l)‐altered pyloric glands (PAPG) and the related induction of adenocarcinomas were examined in male C3H mice given N‐methyl‐N‐nitrosourea (MNU) in their drinking water at the concentration of 120 ppm (group 1), 60 ppm (group 2...

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Detalles Bibliográficos
Autores principales: Yamamoto, Masami, Furihata, Chie, Fujimitsu, Yasunobu, Imai, Toshio, Inada, Ken‐ichi, Nakanishi, Hayao, Tatematsu, Masae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921371/
https://www.ncbi.nlm.nih.gov/pubmed/9140107
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00373.x