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Mutational Analysis of BRCA1 Gene in Ovarian and Breast‐ovarian Cancer Families in Japan

We analyzed the alteration of BRCAI in DNA obtained from 83 individuals of 13 Japanese site‐specific ovarian cancer families and 6 breast‐ovarian cancer families. Six germline mutations were detected in 7 families, which consisted of 4 breast‐ovarian cancer and 3 site‐specific ovarian cancer familie...

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Detalles Bibliográficos
Autores principales: Takano, Masashi, Aida, Hiroshi, Tsuneki, Ikunosuke, Takakuwa, Koichi, Hasegawa, Isao, Tanaka, Hajime, Saito, Masaaki, Tsuji, Shoji, Sonoda, Takahiko, Hatae, Masayuki, Chen, Jui‐Tung, Takahashi, Katsuyuki, Hasegawa, Kazuo, Toyoda, Nagayasu, Saito, Noriyasu, Yakushiji, Michiaki, Araki, Tsutomu, Tanaka, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921420/
https://www.ncbi.nlm.nih.gov/pubmed/9197534
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00397.x