Effect of CPT‐11 on Lipid Peroxide Level in Mouse Tissues

We examined the effects of CPT‐11 on lipid peroxide level and glutathione peroxidase (GSHpx) activity as indices of the toxicity of this antitumor agent in mouse and rat tissues. After CPT‐11 (100 mg/kg, i.p.) administration, the lipid peroxide level in the heart increased 1.5 fold (mice) and 1.3 fo...

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Detalles Bibliográficos
Autores principales: Sadzuka, Yasuyuki, Hirota, Sadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921459/
https://www.ncbi.nlm.nih.gov/pubmed/9247609
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00411.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921459/
https://www.ncbi.nlm.nih.gov/pubmed/9247609
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00411.x

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