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Effect of CPT‐11 on Lipid Peroxide Level in Mouse Tissues
We examined the effects of CPT‐11 on lipid peroxide level and glutathione peroxidase (GSHpx) activity as indices of the toxicity of this antitumor agent in mouse and rat tissues. After CPT‐11 (100 mg/kg, i.p.) administration, the lipid peroxide level in the heart increased 1.5 fold (mice) and 1.3 fo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
1997
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921459/ https://www.ncbi.nlm.nih.gov/pubmed/9247609 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00411.x |