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Retroviral Introduction of the p16 Gene into Murine Cell Lines to Elicit Marked Antiproliferative Effects
The pl6 gene is a candidate tumor suppressor, because mutation of the gene has been reported in many transformed cell lines and some primary tumor tissues. We have examined this possibility in murine cell lines (NIH3T3 and RSV‐M) which lack pl6 gene expression. Full‐length human p16 cDNA was obtaine...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1997
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921492/ https://www.ncbi.nlm.nih.gov/pubmed/9330601 http://dx.doi.org/10.1111/j.1349-7006.1997.tb00441.x |