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Retroviral Introduction of the p16 Gene into Murine Cell Lines to Elicit Marked Antiproliferative Effects

The pl6 gene is a candidate tumor suppressor, because mutation of the gene has been reported in many transformed cell lines and some primary tumor tissues. We have examined this possibility in murine cell lines (NIH3T3 and RSV‐M) which lack pl6 gene expression. Full‐length human p16 cDNA was obtaine...

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Detalles Bibliográficos
Autores principales: Ikeda, Hiroshi, Yoshida, Jun, Yamada, Hitoshi, Yoshimatsu, Tadanori, Ikenaka, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921492/
https://www.ncbi.nlm.nih.gov/pubmed/9330601
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00441.x