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N(G)‐Nitro‐L‐arginine Methyl Ester Inhibits Bone Metastasis after Modified Intracardiac Injection of Human Breast Cancer Cells in a Nude Mouse Model

We investigated the effects of N(G)‐nitro‐L‐arginine‐methyI ester (L‐NAME), a nitric oxide synthase (NOS) inhibitor, on hone metastasis of human breast cancer, MDA‐231 cells. Tumor cells (2 × 10(5) cells in 0.2 ml of phosphate‐buffered saline; PBS) were injected through the diaphragm into the left v...

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Detalles Bibliográficos
Autores principales: Iwasaki, Teruo, Higashiyama, Masahiko, Kuriyama, Keiko, Sasaki, Akira, Mukai, Mutsuko, Shinkai, Kiyoko, Horai, Takeshi, Matsuda, Hikaru, Akedo, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921518/
https://www.ncbi.nlm.nih.gov/pubmed/9369934
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00462.x