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Effects of Bioreductive Agents, Tirapazamine and Mitomycin C, on Quiescent Cell Populations in Solid Tumors, Evaluated by Micronucleus Assay

Mice bearing transplantable solid tumors received 10 intraperitoneal administrations of 5‐bromo‐2′‐deoxyuridine (BrdU) to label the proliferating (P) tumor cells, and were then irradiated with (60)Cogamma‐rays or injected with cis‐diamminedichloroplatinum (II) (cisplatin). The tumor cells were isola...

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Detalles Bibliográficos
Autores principales: Masunaga, Shin‐ichiro, Ono, Koji, Hori, Hitoshi, Shibata, Toru, Suzuki, Minoru, Kinashi, Yuko, Takagaki, Masao, Akaboshi, Mitsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921522/
https://www.ncbi.nlm.nih.gov/pubmed/9369940
http://dx.doi.org/10.1111/j.1349-7006.1997.tb00468.x