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Endothelial AIP1 Regulates Vascular Remodeling by Suppressing NADPH Oxidase-2

Objective: AIP1 expression is downregulated in human atherosclerotic plaques and global deletion of AIP1 in mice exacerbates atherosclerosis in ApoE-KO mouse models. However, the direct role of AIP1 in endothelium, vascular remodeling and associated vascular diseases has not been determined. Approac...

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Detalles Bibliográficos
Autores principales: Zhang, Jiqin, Chen, Chaofei, Li, Li, Zhou, Huanjiao J., Li, Fenghe, Zhang, Haifeng, Yu, Luyang, Chen, Yuxin, Min, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921534/
https://www.ncbi.nlm.nih.gov/pubmed/29731721
http://dx.doi.org/10.3389/fphys.2018.00396