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Frameshift Mutations of the hMSH6 Gene in Human Leukemia Cell Lines

Defects in DNA mismatch repair mechanisms, including frameshift mutations of the hMSH6 and hMSH3 genes at their (C)(8) and (A)(8) tracks, respectively, have been shown to be associated with human malignancies. To clarify the possible involvement of these mutations in hematopoietic malignancies, we s...

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Detalles Bibliográficos
Autores principales: Hosoya, Noriko, Hangaishi, Akira, Ogawa, Seishi, Miyagawa, Kiyoshi, Mitani, Kinuko, Yazaki, Yoshio, Hirai, Hisamaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921588/
https://www.ncbi.nlm.nih.gov/pubmed/9510473
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00476.x