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Adeno‐associated Virus Vector Containing the Herpes Simplex Virus Thymidine Kinase Gene Causes Complete Regression of Intracerebrally Implanted Human Gliomas in Mice, in Conjunction with Ganciclovir Administration

Adeno‐associated virus (AAV) has attracted considerable interest as a potential vector for gene therapy because of its wide host range, high transduction efficiency, and lack of cytopathogenicity. In this experiment, we evaluated the efficacy of AAV vector containing the herpes simplex virus thymidi...

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Detalles Bibliográficos
Autores principales: Mizuno, Masaaki, Yoshida, Jun, Colosi, Peter, Kurtzman, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921591/
https://www.ncbi.nlm.nih.gov/pubmed/9510479
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00482.x