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Different Effects of FK317 on Multidrug‐resistant Tumor in vivo and in vitro

FK317, a novel substituted dihydrobenzoxazine, was examined for antitumor effects on multidrug‐resistant (MDR) tumor cells in vitro and in vivo. In nude mice, FK317 markedly inhibited the growth of s.c. implanted KB‐V1 vinblastine (VLB)‐resistant human epidermal carcinoma KB cells, as well as the pa...

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Detalles Bibliográficos
Autores principales: Naoe, Yoshinori, Inami, Masamichi, Takagaki, Shoji, Matsumoto, Sanae, Kawamura, Ikuo, Nishigaki, Fusako, Tsujimoto, Susumu, Manda, Toshitaka, Shimomura, Kyoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921702/
https://www.ncbi.nlm.nih.gov/pubmed/9849584
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00495.x