Relationship between Protein Levels and Gene Expression of Dihydropyrimidine Dehydrogenase in Human Tumor Cells during Growth in Culture and in Nude Mice

Protein levels and gene expression of dihydropyrimidine dehydrogenase (DPD), the rate‐limiting enzyme for degradation of 5‐fluorouracil, were studied in two human tumor cell lines (fibrosarcoma HT‐1080 and pancreatic carcinoma MIAPaCa‐2) in various growth phases of the cultured cells and of tumor xe...

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Detalles Bibliográficos
Autores principales: Takechi, Teiji, Okabe, Hiroyuki, Fujioka, Akio, Murakami, Yuko, Fukushima, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921712/
https://www.ncbi.nlm.nih.gov/pubmed/9914783
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00509.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921712/
https://www.ncbi.nlm.nih.gov/pubmed/9914783
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00509.x

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