Lithocholic Acid, a Putative Tumor Promoter, Inhibits Mammalian DNA Polymerase β

Lithocholic acid (LCA), one of the major components in secondary bile acids, promotes carcinogenesis in rat colon epithelial cells induced by N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG), which methylates DNA. Base‐excision repair of DNA lesions caused by the DNA methylating agents requires DNA polym...

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Detalles Bibliográficos
Autores principales: Ogawa, Akio, Murate, Takashi, Suzuki, Motoshi, Nimura, Yuji, Yoshida, Shonen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921720/
https://www.ncbi.nlm.nih.gov/pubmed/9914784
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00510.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921720/
https://www.ncbi.nlm.nih.gov/pubmed/9914784
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00510.x

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