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Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P‐Glycoprotein

The inhibitory effects of SDZ PSC 833 (PSC833), a non‐immunosuppressive cyclosporin derivative, on the P‐glycoprotein (P‐gp)‐mediated transport of doxorubicin and vinblastine were compared with those of cyclosporin A (Cs‐A). The transcellular transport of the anticancer drugs and PSC833 across a mon...

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Detalles Bibliográficos
Autores principales: Kusunoki, Nobuya, Takara, Kohji, Tanigawara, Yusuke, Yamauchi, Aiko, Ueda, Kazumitsu, Komada, Fusao, Ku, Yonson, Kuroda, Yoshikazu, Saitoh, Yohichi, Okumura, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921725/
https://www.ncbi.nlm.nih.gov/pubmed/9914792
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00518.x