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Targeted Gene Transfer for Adenocarcinoma Using a Combination of Tumor‐specific Antibody and Tissue‐specific Promoter

We have developed a highly specific gene transfer method for adenocarcinoma using a monoclonal antibody against tumor‐specific antigen coupled with a plasmid containing the carcinoembryonic antigen (CEA)‐specific promoter. The chimeric CEA promoter (CC promoter), which contained an enhancer from the...

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Detalles Bibliográficos
Autores principales: Kurane, Shuji, Krauss, John C., Watari, Eiji, Kannagi, Reiji, Chang, Alfred E., Kudoh, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921727/
https://www.ncbi.nlm.nih.gov/pubmed/9914791
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00517.x