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Growth Inhibition, Enhancement of Intercellular Adhesion, and Increased Expression of Carcinoembryonic Antigen by Overexpression of Phosphoinositides‐specific Phospholipase C β1 in LS174T Human Colon Adenocarcinoma Cell Line

By using a retrovirus‐derived system we generated derivatives of the human colon adenocarcinoma cell line LS174T (ATCC CL 188) that stably overexpress a full‐length cDNA encoding the β1 isoform of bovine phosphoinositides‐specific phospholipase C (PI‐PLC). This was confirmed by the elevated levels o...

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Detalles Bibliográficos
Autores principales: Nomoto, Koji, Tomita, Naohiro, Miyake, Masami, Xhu, Ding‐Bang, LoGerfo, Paul R., Weinstein, I. Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921740/
https://www.ncbi.nlm.nih.gov/pubmed/10081486
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00522.x