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Suppression of Anti‐microtubule Agent‐induced Apoptosis by Nitric Oxide: Possible Mechanism of a New Drug Resistance

The propensity of a cell to undergo apoptosis has been proposed to be a determinant of sensitivity to anti‐microtubule agents. The anti‐microtubule agents vincristine and paclitaxel induce key features of apoptosis, such as intranucleosomal DNA fragmentation and changes in nuclear morphology in the...

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Detalles Bibliográficos
Autores principales: Ogura, Tsutomu, DeGeorge, George, Tatemichi, Masayuki, Esumi, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921764/
https://www.ncbi.nlm.nih.gov/pubmed/9548448
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00549.x