1‐Methyl‐3‐propyl‐7‐butylxanthine, a Novel Biochemical Modulator, Enhances Therapeutic Efficacy of Adriamycin

We have screened xanthine derivatives for activity as novel biochemical modulators by assay of their inhibitory effect on adriamycin efflux from tumor cells. Strong inhibition of adriamycin efflux was shown by some xanthine derivatives with various alkyl or oxoalkyl substituents at the 1‐, 3‐ and 7‐...

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Detalles Bibliográficos
Autores principales: Sadzuka, Yasuyuki, Iwazaki, Ayano, Sugiyama, Tomomi, Sawanishi, Takayuki, Miyamoto, Ken‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921768/
https://www.ncbi.nlm.nih.gov/pubmed/9548452
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00553.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921768/
https://www.ncbi.nlm.nih.gov/pubmed/9548452
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00553.x

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