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1‐Methyl‐3‐propyl‐7‐butylxanthine, a Novel Biochemical Modulator, Enhances Therapeutic Efficacy of Adriamycin
We have screened xanthine derivatives for activity as novel biochemical modulators by assay of their inhibitory effect on adriamycin efflux from tumor cells. Strong inhibition of adriamycin efflux was shown by some xanthine derivatives with various alkyl or oxoalkyl substituents at the 1‐, 3‐ and 7‐...
Autores principales: | Sadzuka, Yasuyuki, Iwazaki, Ayano, Sugiyama, Tomomi, Sawanishi, Takayuki, Miyamoto, Ken‐ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921768/ https://www.ncbi.nlm.nih.gov/pubmed/9548452 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00553.x |
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