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Early Phase Tumor Accumulation of Macromolecules: A Great Difference in Clearance Rate between Tumor and Normal Tissues

The objective of this study was to investigate the molecular weight (MW) and time‐dependence of the phenomenon termed “the enhanced permeability and retention”(EPR) effect in solid tumor, in particular to determine and define the early phase accumulation of macromolecules in tumor and normal tissues...

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Detalles Bibliográficos
Autores principales: Noguchi, Youichiro, Wu, Jun, Duncan, Ruth, Strohalm, Jiří, Ulbrich, Karel, Akaike, Takaaki, Maeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921799/
https://www.ncbi.nlm.nih.gov/pubmed/9600125
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00563.x