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Inhibition of Cyclin D1 Expression and Induction of Apoptosis by Inostamycin in Small Cell Lung Carcinoma Cells

Previously, we demonstrated that inostamycin, an inhibitor of phosphatidylinositol turnover, caused cell cycle arrest at the G1 phase, inhibiting the expression of cyclins D1 and E in normal cells. In the present study, we examined the effects of inostamycin on cell cycle progression and apoptosis i...

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Detalles Bibliográficos
Autores principales: Imoto, Masaya, Tanabe, Keiko, Simizu, Siro, Tashiro, Etsu, Takada, Minoru, Umezawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921804/
https://www.ncbi.nlm.nih.gov/pubmed/9600126
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00564.x