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Increased Sensitivity to Long‐term 5‐Fluorouracil Exposure of Human Colon Cancer HT‐29 Cells Resistant to Short‐term Exposure
A 5‐fluorouracil (5‐FU)‐resistant subline of human colon cancer HT‐29 cells was developed by repeated 1‐h exposure in vitro to 5‐FU. This subline (HT‐29/5‐FU/S) had 8‐fold resistance to 5‐FU in a 1‐h exposure assay. However, it had rather increased sensitivity to 5‐FU when assayed after a continuous...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921808/ https://www.ncbi.nlm.nih.gov/pubmed/9600127 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00565.x |