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Increased Sensitivity to Long‐term 5‐Fluorouracil Exposure of Human Colon Cancer HT‐29 Cells Resistant to Short‐term Exposure

A 5‐fluorouracil (5‐FU)‐resistant subline of human colon cancer HT‐29 cells was developed by repeated 1‐h exposure in vitro to 5‐FU. This subline (HT‐29/5‐FU/S) had 8‐fold resistance to 5‐FU in a 1‐h exposure assay. However, it had rather increased sensitivity to 5‐FU when assayed after a continuous...

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Detalles Bibliográficos
Autores principales:	Inaba, Makoto, Tanaka, Tomoko, Sawada, Hiroko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921808/ https://www.ncbi.nlm.nih.gov/pubmed/9600127 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00565.x

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