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Attenuation of TGFBR2 expression and tumour progression in prostate cancer involve diverse hypoxia-regulated pathways

BACKGROUND: Dysregulation of transforming growth factor β (TGF-β) signaling and hypoxic microenvironment have respectively been reported to be involved in disease progression in malignancies of prostate. Emerging evidence indicates that downregulation of TGFBR2, a pivotal regulator of TGF-β signalin...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Wu, Guanqing, Ma, Xueyou, Xiao, Jun, Yu, Gan, Yang, Chunguang, Xu, Nan, Zhang, Bao, Zhou, Jun, Ye, Zhangqun, Wang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921809/
https://www.ncbi.nlm.nih.gov/pubmed/29699590
http://dx.doi.org/10.1186/s13046-018-0764-9