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Suppressive Effect of Irsogladine Maleate on Diethylnitrosamine‐initiated and Phenobarbital‐promoted Hepatocarcinogenesis in Male F344 Rats

Modifying effects of irsogladine maleate (IRG) on diethylnitrosamine (DEN)‐induced hepatocarcinogenesis were examined in male F344 rats. Six‐week‐old rats were divided into 8 groups. Groups 1 through 4 were given a single i.p. injection of DEN (200 mg/kg body weight) at the start of the experiment,...

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Detalles Bibliográficos
Autores principales: Sugie, Shigeyuki, Okamoto, Kiyohisa, Ueda, Fusao, Watanabe, Tomoyuki, Tanaka, Takuji, Mori, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921819/
https://www.ncbi.nlm.nih.gov/pubmed/9617341
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00573.x