Epitope Blocking: Positive and Negative Effects on the Biodistribution of (125)I‐Labeled Anti‐Tac Disulfide‐stabilized Fv Fragment of Two Antibodies against Different Epitopes of the Circulating Antigen

Prior in vivo studies using the (125)I‐labeled anti‐Tac disulfide‐stabilized variable region fragment ((125)I‐anti‐Tac dsFv) of monoclonal antibody in the presence of the circulating soluble alpha subunit of the interleukin‐2 receptor (sIL‐2Rα) have shown formation of complexes which interfere with...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hisataka, Sun, Bao‐Fu, Han, Eui‐Sik, Kim, Meyoung‐Kon, Le, Nhat, Wang, Qing‐Cheng, Nelson, David L., Pastan, Ira, Waldmann, Thomas A., Paik, Chang H., Carrasquillo, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921826/
https://www.ncbi.nlm.nih.gov/pubmed/9617350
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00582.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921826/
https://www.ncbi.nlm.nih.gov/pubmed/9617350
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00582.x

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