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Epitope Blocking: Positive and Negative Effects on the Biodistribution of (125)I‐Labeled Anti‐Tac Disulfide‐stabilized Fv Fragment of Two Antibodies against Different Epitopes of the Circulating Antigen
Prior in vivo studies using the (125)I‐labeled anti‐Tac disulfide‐stabilized variable region fragment ((125)I‐anti‐Tac dsFv) of monoclonal antibody in the presence of the circulating soluble alpha subunit of the interleukin‐2 receptor (sIL‐2Rα) have shown formation of complexes which interfere with...
Autores principales: | Kobayashi, Hisataka, Sun, Bao‐Fu, Han, Eui‐Sik, Kim, Meyoung‐Kon, Le, Nhat, Wang, Qing‐Cheng, Nelson, David L., Pastan, Ira, Waldmann, Thomas A., Paik, Chang H., Carrasquillo, Jorge A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921826/ https://www.ncbi.nlm.nih.gov/pubmed/9617350 http://dx.doi.org/10.1111/j.1349-7006.1998.tb00582.x |
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