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Association of Loss of Heterozygosity at the p53 Locus with Chemoresistance in Osteosarcomas

Although the osteosarcoma is considered to be among the most chemosensitive malignancies and preoperative chemotherapy is commonly applied, an appreciable proportion of cases are in fact quite insensitive. Predictive markers for chemosensitivity are therefore desirable in order to develop effective...

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Detalles Bibliográficos
Autores principales: Goto, Akiteru, Kanda, Hiroaki, Ishikawa, Yuichi, Matsumoto, Seiichi, Kawaguchi, Noriyoshi, Machinami, Rikuo, Kato, Yo, Kitagawa, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921844/
https://www.ncbi.nlm.nih.gov/pubmed/9685858
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03295.x