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Cell Cycle‐dependent Modulation of Promoter Activities of RB and WAF1/Cip1 Genes

A universal inhibitor of cyclin‐dependent kinases, WAF1/Cip1 can dephosphorylate the RB gene product to arrest the cell cycle at the G1 phase. Here we show that the mRNA level and the promoter activities of the RB and WAF1/Cip1 genes exhibit cell cycle‐dependent change when cells are released from e...

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Detalles Bibliográficos
Autores principales: Matsumoto, Takuji, Ohtani‐Fujita, Naoko, Sowa, Yoshihiro, Bai, Fulu, Nikaido, Toshio, Tamaki, Tetsuya, Sakai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921868/
https://www.ncbi.nlm.nih.gov/pubmed/9703360
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03264.x