Neoplastic Transformation of Rat Colon Epithelial Cells by Expression of Activated Human K‐ras

Somatic mutations of the K‐ras oncogene play an important role in colorectal carcinogenesis. We determined whether rat colon epithelial cells could be transformed by introducing retroviruses carrying the activated human K‐ras oncogene alone. Primary epithelial cells from the rat distal colon were in...

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Detalles Bibliográficos
Autores principales: Sugiyama, Kenji, Otori, Kazuhiko, Esumi, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921874/
https://www.ncbi.nlm.nih.gov/pubmed/9703359
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03263.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921874/
https://www.ncbi.nlm.nih.gov/pubmed/9703359
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03263.x

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