Cytotoxic Mechanisms of FK317, a New Class of Bioreductive Agent with Potent Antitumor Activity

FK317 is a member of a new class of bioreductive agents that exhibit strong cytotoxicity against various human cancer cells. The effect of FK317 was found to be stronger than that of mitomycin C (MMC), adriamycin (ADR) or cisplatin (CDDP). Alkaline elution analysis indicated that FK317 formed inters...

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Detalles Bibliográficos
Autores principales: Naoe, Yoshinori, Inami, Masamichi, Kawamura, Ikuo, Nishigaki, Fusako, Tsujimoto, Susumu, Matsumoto, Sanae, Manda, Toshitaka, Shimomura, Kyoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921879/
https://www.ncbi.nlm.nih.gov/pubmed/9703365
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03269.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921879/
https://www.ncbi.nlm.nih.gov/pubmed/9703365
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03269.x

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