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Fas and Mutant Estrogen Receptor Chimeric Gene: A Novel Suicide Vector for Tamoxifen‐inducible Apoptosis
Several cancer gene therapy strategies involve suicide genes to kill the neoplasm, or to regulate effector cells such as lymphocytes. We have developed an inducible apoptosis system with a Fasestrogen receptor fusion protein (MfasER) for rapid elimination of transduced cells. In the present study, w...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921882/ https://www.ncbi.nlm.nih.gov/pubmed/9738981 http://dx.doi.org/10.1111/j.1349-7006.1998.tb03279.x |