Cargando…

Fas and Mutant Estrogen Receptor Chimeric Gene: A Novel Suicide Vector for Tamoxifen‐inducible Apoptosis

Several cancer gene therapy strategies involve suicide genes to kill the neoplasm, or to regulate effector cells such as lymphocytes. We have developed an inducible apoptosis system with a Fasestrogen receptor fusion protein (MfasER) for rapid elimination of transduced cells. In the present study, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Kodaira, Hiroshi, Kume, Akihiro, Ogasawara, Yoji, Urabe, Masashi, Kitano, Kiyoshi, Kakizuka, Akira, Ozawa, Keiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921882/
https://www.ncbi.nlm.nih.gov/pubmed/9738981
http://dx.doi.org/10.1111/j.1349-7006.1998.tb03279.x