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Differential Expression of DNA Topoisomerase IIα and IIβ Genes between Small Cell and Non‐small Cell Lung Cancer

DNA topoisomerase II (Topo II) inhibitors are widely used in lung cancer chemotherapy, but small cell lung cancer (SCLC) and non‐small cell lung cancer (NSCLC) show different sensitivity to them. In this study, we examined the gene expression levels of both isoforms of Topo II (IIα and IIβ) in lung...

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Detalles Bibliográficos
Autores principales: Syahruddin, Elisna, Oguri, Tetsuya, Takahashi, Toshiaki, Isobe, Takeshi, Fujiwara, Yasuhiro, Yamakido, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921913/
https://www.ncbi.nlm.nih.gov/pubmed/9765623
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00640.x